CTSI releases RFA for the successful preparation, implementation of prospective pilot clinical studies

Published by CTSI on March 15, 2019

Young business man completing paperworkCTSI has released a Request for Applications for its Clinical and Translational Research Services (CTRS) Pilot Funding Program, which provides funding in two stages to full-time University of Minnesota faculty to prepare and implement prospective clinical pilot studies. It is expected that data gathered through this funding mechanism will be used to inform the design of subsequent larger clinical trials. 


Planning prospective clinical pilot study (Stage I)

Stage I Pilot awardees are expected to successfully assemble a study team, prepare an Institutional Review Board (IRB) application, and secure IRB and National Center for Advancing Translational Sciences (NCATS) approvals within four to six months of award date. CTSI anticipates funding between two and five projects and up to $5,000 will be awarded to each project to cover the costs of biostatistical support and coordinator time, if applicable.

CTSI experts in the Clinical Research Support Center can provide additional guidance and support throughout this Stage at no cost to the investigator, however these experts are not be available to coordinate the study.

For this funding program, a prospective pilot clinical study is a research study in which one or more human subjects are prospectively assigned to one or more interventions, with or without a placebo or other control, to evaluate methods and procedures to be used in a subsequent larger clinical trial.

Implementing prospective clinical pilot study

The goal of Stage I is to prepare for Stage II, which includes the successful implementation and completion of the proposed prospective pilot clinical study. Stage II projects are to be completed within 18 months. It is expected that successful completion of Stage II will lead to at least one peer-reviewed publication to be submitted within one year.

Projects funded through Stage II are typically awarded $25,000 to $75,000, with smaller awards as needed.

Eligibility for Stage II funding is contingent on successful completion of Stage I.

Learn more about previously funded projects through this program.

Mandatory Letters of Intent are due by 5pm, April 1. Requests for full proposals will be sent by invitation only approximately three weeks following receipt of LOIs.

View the Request for Application

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