Translational Research Development Program

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ctsieduc@umn.edu
612-626-1566

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Related event

Think Like a Researcher Workshop Series, for UMN undergraduates interested in pursuing a research career

The Translational Research Development Program (TRDP) aims to provide an opportunity for early stage investigators to gain significant experience with clinical and translational research.

The program is available to predoctoral trainees, postdoctoral trainees and medical fellows and provides research funds up to $16,000 available over two years.

Program overview 

  • Expanded its eligibility criteria and is available to:
    • Predoctoral trainees pursuing a PhD in a PhD graduate program or PhD dual degree program who have passed their written and oral preliminary examinations
    • Postdoctoral trainees, including medical fellows, who are no more than 3 years into their postdoctoral training.
  • Aims to provide an opportunity for early stage investigators to gain significant experience with clinical and translational research.
  • Research funds up to $16,000 available over two years
  • Requires a primary research mentor and a translational mentor, such as a senior faculty member or biostatistician, who will help guide and advise the TRDP project

Application details 

This program is not currently accepting applications. View application information from the previous cycle:

Program deadlines

This program is not currently accepting applications. View deadlines from the previous cycle:

  • February 12, 2015 (noon): LOI due
  • February 19, 2015: Invite full proposals
  • April 2, 2015 (noon): Full proposals due
  • June 1, 2015: Program start date  

Nature and purpose of this RFA

The Clinical and Translational Science Institute (CTSI) will provide institutional research funds for predoctoral and postdoctoral trainees with a demonstrable and significant interest in clinical or translational research focused on human health. The program aims to provide an opportunity for early stage investigators to gain significant experience with clinical and translational research as a foundation for the development of an independent research career focused on human health.

Funds are designed to support a modest research project that will result in a publication in a peer reviewed journal. The TRDP project is secondary to the applicant’s primary research endeavors and must advance the trainee’s research along the clinical and translational research spectrum (see below). For example, a TRDP project for a trainee currently conducting basic research (T0) should be in the T1, T2, T3, or T4 translational categories. Similarly, a trainee currently conducting health services research (T3) should develop a TRDP project that demonstrates a clear movement toward the T4 category.

Current scholars

Mariam Ahmed, MS

Primary mentor: Richard Brundage
Additional mentor: Gerald Raymond
Project title: A Model-based Approach to Optimize Lorenzo's Oil Therapy in X-Linked Adrenoleukodystrophy


Tyler Bosch, PhD

Primary mentor: Lisa Chow
Additional mentor: Patrick Bolan
Project title: The Effect of High Intensity Interval Training on Liver Fat and Insulin Sensitivity in Adults with Obesity


Nicholas Brady

Primary mentor: Kathryn Schwertfeger
Additional mentor: Douglas Yee
Project title: JAK Inhibition Disrupts Inflammatory Homeostasis in Human Macrophages


Michael Burns, PhD

Primary mentor: Ran Blekhman
Additional mentor: Timothy Church
Project title: Using Virulence Genes in Stool as Markers of Colorectal Cancer


Jeff Flynn, PhD

Primary mentor: Ryan Hunter
Additional mentor: Jordan Dunitz
Project title: Anaerobic bacterial consortia sustain the growth of pathogens in the upper airways of cystic fibrosis patients


Diego Garcia-Huidobro, MD

Primary mentor: Michele Allen
Additional mentor: Iris Borowsky
Project title: Feasibility of a One-To-One Parenting Intervention to Prevent Substance Use in Latino Youth


Christopher Janson, MD

Primary mentor: Cornelius Lam
Additional mentor: Gunda Georg
Project title: High-Throughput Discovery with Unique Alzheimer's Cellular Model


Sakeen Kashem, BA

Primary mentor: Daniel Kaplan
Additional mentor: Maria Hordinksy
Project title: Langerhans cell function in controlling fungal immunity and commensalism


Liliane Mukaremera, PhD

Primary mentor: Kirsten Nielsen
Additional mentor: David Boulware
Project title: Alteration of the innate immune response by different Cryptococcus neoformans morphologies in HIV and healthy individuals


Emily Pisetsky, PhD

Primary mentor: Scott Crow
Additional mentor: Jim Hodges
Project title: Negative Affect and Substance Use as Momentary Mechanisms of Suicidality in Eating Disorders


Justin Ryder, PhD

Primary mentor: Aaron S. Kelly
Additional mentor: Kyle Rudser
Project title: Longitudinal assessment of novel biomarkers for predicting cardiovascular disease in youth


Anja Srienc

Primary mentor: Eric Newman
Additional mentor: Matthew Hunt
Project title: Cortical Spreading Depression as a Biomarker of Brain Injury During Neurosurgery


Alena Svatkova, MD

Primary mentor: Igor Nestrasil
Additional mentor: Kyle Rudser
Project title: Revealing the Core of White Matter Alteration and Cognitive Deficits in Mucopolysaccharidosis Type 2


Elizabeth Thompson, MS

Primary mentor: Eric A. Hendrickson
Additional mentor: Jakub Tolar
Project title: Gene therapy for Fanconi anemia using Cas9/CRISPR-mediated gene targeting


Diana Wallin, BS

Primary mentor: Michael K. Georgieff
Additional Mentor: Gregory Vercellotti
Project title: The effect of recombinant human erythropoietin (RhEpo) therapy on the hippocampus of anemic neonatal mice


Tonya Ward, PhD

Additional mentor: Cheryl A. Gale
Project title: Infant Fungal Microbiome and Allergic Disease Development


Andrea Wolf, BS

Primary mentor: Greg Beilman
Additional mentor: Raj Suryanarayanan
Project title: Formulation Optimization of a Low-Volume Resuscitation Fluid for Hemorrhagic Shock

Former scholars

Daniel Beisang, BS

Primary mentor: Michael Georgieff
Additional mentor: Marc Jenkins
Project title: Quantitative Assessment of the Diversity of the Neonatal T cell Repertoire


Caroline Diep, BS, BA

Primary mentor: Peter Argenta
Additional mentor: Carol Lange
Project title: En vivo modeling of primary ovarian cancer cells in 3D culture systems


Anne Frosch, MD

Primary mentor: George Ayodo
Additional mentor: Chandy John
Project title: The effect of HIV infection on malaria specific B cell subset frequency


Benjamin Hanisch, MD

Primary mentor: Gregory Vercellotti
Additional mentor: Chandy John 
Project title: Impact of Iron Supplementation on Oxidative Stress in Children Recovering from Severe Malaria


Rachel Hardeman, PhD, MPH 

Primary mentor: Diana Burgess
Additional mentor: Katy Kozhimannil
Project title: Racial/Ethnic Disparities in Birth Outcomes: Examining the Role of the Patient/Provider Relationship


David Knorr, BS

Primary mentor: Michael Verneris
Additional mentor: Todd DeFor
Project title: Evaluation of the CD4+ T cell response against influenza following hematopoietic cell transplantation


Jessica Musselman, MS

Primary mentor: Julie Ross
Additional mentor: Jenny Poynter
Project title: Methylation of the BMP/TGFβ pathway and correlation with survival in childhood germ cell tumors


Alexa Pragman, MD, PhD (current CTSI KL2 scholar)

Primary mentor: Chris Wendt
Additional mentors: Richard Isaacson and Cavan Reilly 
Project title: Comparison of the Oral and Lung Microbiota in Chronic Obstructive Pulmonary Disease


Brent Sorenson, MS

Primary mentor: Rajaram Gopalakrishnan
Additional mentor: Mark Herzberg
Project title: Tumor-targeted reduction of hyopxia-inducible factor in oral carcinoma by calprotectin


Alexa Weingarden, BA

Primary mentor: Alexander Khoruts
Additional mentor: Michael Sadowsky
Project title: Bacterial Bile Acid Metabolism in Fecal Transplantation Treatment of Clostridium difficile Infection