Trial Innovation Network (TIN)

A collaborative national network for multi-site clinical trials that focuses on operational innovation, excellence, and collaboration.

The National Institutes of Health (NIH) launched the Trial Innovation Network (TIN) in 2017 to help researchers carry out multicenter clinical trials better, faster and more cost-efficiently, and to create a national laboratory to study, understand and innovate the process of conducting clinical trials. 

The Trial Innovation Network aims to develop, demonstrate effectiveness of, and disseminate scientific and operational innovations that dramatically increase the effectiveness of clinical studies. It features a single IRB system, master contracting agreements, quality by design approaches, and focuses on evidence-based strategies for recruitment and patient engagement.

Researchers who are interested in bringing new interventions to patients and communities more effectively and efficiently should be interested in the collaborations and opportunities TIN provides. 

TIN resources available to UMN investigators

The network offers University of Minnesota investigators access to a broad range of services and consultations to improve the way they create and conduct clinical trials and studies, including:

  • Help with trial planning
  • Recruitment feasibility assessment and recruitment tools
  • Cohort discovery by electronic health record
  • Assistance with site selection
  • Single IRB review for all sites
  • Standardized agreement

Characteristics of ideal TIN proposals

The Trial Innovation Network invites proposals from University of Minnesota investigators who are considering developing study proposals with:

  • Multi-center study design (three or more institutions)
  • Willingness to partner with the TIN through the lifecycle of the project
  • An innovative operational approach to improve quality, efficiency, or cost of clinical research
  • At least 60 days allotted for consultation prior to planned grant submission with substantial project development
  • All populations affected by the health condition being studied, including women, racial/ethnic minorities and children
  • The ability to provide academic evidence to improve clinical trial designs, conduct, and reportability

TIN brings together Clinical and Translational Science Award (CTSA) Program Hubs from across the country, Trial Innovation Centers (TICs), and the Recruitment Innovation Center (RIC) to innovatively address critical roadblocks in clinical trials and accelerate the translation of novel interventions into life-saving therapies. As a CTSA center, the University of Minnesota's CTSI is a hub of the Trial Innovation Network. 

Learn more about TIN or discuss a multi-site clinical trial with the UMN TIN Liaison Team

Trial Innovation Network (TIN)

Contact the UMN TIN Liaison Team

Françoise Crevel, PharmD
Lead Clinical Research Specialist, Clinical Translational Research Services (CTRS)

Brenda Prich, MHA, BSN, RN, CCRC
Associate Director, CTRS

Stop by the Clinical Research Support Center (CRSC) in 330 Diehl Hall (Bio-Medical Library)

Dan Weisdorf, MD
TIN Medical Director